The ultimate RSO dosage guide for 2025. Includes printable dosage chart, beginner protocols, 90-day treatment protocol, microdosing tips, tolerance breaks, and condition-specific dosing.
RSO 90-Day Protocol
The standard RSO protocol developed by Rick Simpson involves gradually increasing doses over 90 days. This allows your body to build tolerance while maximizing therapeutic benefits.
| Week | Daily Dose | Doses/Day | Notes |
|---|---|---|---|
| 1-3 | 25-50mg total | 3 | Rice grain size, build tolerance |
| 4-5 | 100-200mg total | 3-4 | Double every 4-5 days |
| 6-8 | 300-500mg total | 3-4 | Continue gradual increase |
| 9-12 | 500-1000mg total | 3-4 | Full therapeutic dose |
Dosing Tips
- • Always take RSO with food containing healthy fats for better absorption
- • Take your largest dose before bed to minimize daytime psychoactive effects
- • Keep a dosing journal to track effects and adjust accordingly
- • Don't increase dose if you're still experiencing strong effects



