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Updated December 12, 2025Medical Reference

Complete Rick Simpson Oil Dosage Guide: 2025 90-Day Protocol Chart

Step-by-step RSO dosing guide for first-time users: rice-grain starting dose, 4-phase protocol, titration schedule, exact weekly increases, and safety tips for the complete 90-day treatment.

Starting RSO is daunting—this guide removes all guesswork. Start low, go slow, and reach your therapeutic dose safely.

Important: Educational Purposes Only

This guide is for educational purposes only. RSO (Rick Simpson Oil) is extremely potent. Always consult a qualified healthcare professional before starting, especially if you are pregnant, nursing, taking medications, or managing a medical condition. Start low, go slow.

RSO Dosage at a Glance

Start

½ rice grain

Night only

Build

1 grain

2–3× daily

Therapeutic

2 grains

3–4× daily

Full Dose

1g per day

Days 61–90

Total for 90-day protocol: ~60 grams

What Is RSO? Quick Overview

Rick Simpson Oil (RSO) is a full-spectrum cannabis extract known for its exceptionally high THC content (60–95%+) and rich cannabinoid profile including CBD, CBG, CBN, and over 200 aromatic terpenes. Created by Rick Simpson in 2003, RSO has become one of the most potent cannabis medicines available.

Because of its extreme potency, precise dosing and gradual dose increases are absolutely critical. Taking too much too fast leads to overwhelming psychoactive effects. The 90-day protocol exists because it works—it allows your body to build tolerance slowly while achieving therapeutic effects safely.

General Principles

Start with a very small dose

Begin with a rice grain size or less

Increase slowly to avoid side effects

Take time between dose increases

Split doses throughout the day

Multiple smaller doses work better than one large dose

Consistency matters more than speed

Regular dosing produces better results

Official 2025 Rick Simpson Oil Dosage Chart

Rick Simpson Oil dosage chart 2025 – complete 90-day protocol with weekly increases from rice grain starting dose
WeeksDaily DoseTotal per WeekNotes
1–2Rice-grain (≈ 0.1g split 3×/day)0.7–1.4 gramsStart low, go slow
3–4Pea-size (≈ 0.25g split 3×/day)1.75–3.5 gramsIncrease only if comfortable
5–121 gram per day (split or night dose)7 gramsMaintenance phase - full dose

Complete 90-Day Treatment: 60 Grams Total

The full Rick Simpson protocol requires 60 grams of RSO over 90 days. This breaks down as follows:

  • • Weeks 1-2: Approximately 1-1.4g total (building tolerance)
  • • Weeks 3-4: Approximately 3.5-7g total (gradual increase)
  • • Weeks 5-12: 7 grams per week × 8 weeks = 56 grams
  • Total: ~60 grams for complete protocol

Our full treatment package provides all 60 grams you need at the best value pricing. Individual results vary - some may complete their protocol in 60-90 days, while others may extend treatment based on their condition and response.

Important Safety Note

Never exceed recommended doses. If you experience discomfort, reduce your dose and slow down the titration. Everyone's tolerance is different. Listen to your body.

How to Measure

Rice Grain Sizes:

  • Rice grain size ≈ very small starting dose
  • Half grain ≈ mid-step
  • Full grain ≈ standard reference

Application Methods:

Use a syringe for accuracy. You may place RSO:

  • • Under the tongue
  • • On food (bread, fruit, yogurt)
  • • Inside an empty capsule

90-Day RSO Dosage Schedule

Phase 1: Introduction & Tolerance Building (Days 1–30)

Goal: Allow the body to adjust

Days 1–5

Dose: ¼ grain of rice

Frequency: Once daily (night)

Days 6–10

Dose: ¼ grain

Frequency: Twice daily (morning & night)

Days 11–15

Dose: ½ grain

Frequency: Twice daily

Days 16–20

Dose: ½ grain

Frequency: Three times daily

Days 21–30

Dose: 1 full grain

Frequency: Three times daily

⚠️ If side effects occur (dizziness, anxiety, nausea), reduce to the previous comfortable dose for several days.

Phase 2: Therapeutic Range (Days 31–60)

Goal: Reach and maintain effective dosing

Days 31–40

Dose: 1 grain

Frequency: 3–4 times daily

Days 41–50

Dose: 1½ grains

Frequency: 3–4 times daily

Days 51–60

Dose: 2 grains

Frequency: 3–4 times daily

Focus on:

  • • Hydration
  • • Light meals
  • • Adequate sleep

Phase 3: Full Protocol / Maintenance (Days 61–90)

Goal: Sustain full therapeutic intake

Days 61–90

Dose: Up to 1 gram per day total

Frequency: Divided into 3–5 doses

Many users reach approximately 60 grams total over 90 days, but this varies by tolerance and individual response.

Tips for Best Results

Avoid alcohol and other intoxicants

Do not drive or operate machinery

Store RSO in a cool, dark place

Keep out of reach of children

Possible Side Effects

These usually lessen as tolerance builds:

• Drowsiness

• Dry mouth

• Dizziness

• Increased appetite

When to Stop or Adjust

Stop or lower your dose if you experience:

  • • Persistent anxiety or panic
  • • Severe nausea or vomiting
  • • Confusion or extreme sedation

Seek medical advice immediately if symptoms are severe.

Final Note

Everyone responds differently to RSO. This 90-day guide emphasizes patience, consistency, and safety. The best results come from listening to your body and progressing at a comfortable pace.

Golden Rules:

  • ✓ Start very small
  • ✓ Increase slowly
  • ✓ Split doses during the day
  • ✓ If it feels too strong, lower the dose

How Much Is One Dose?

Use the size of a grain of rice as your reference:

  • ¼ grain = very tiny (starter dose)
  • ½ grain = small
  • 1 grain = standard

You can place RSO:

  • • Under the tongue
  • • On food (bread, fruit, yogurt)
  • • Inside an empty capsule

90-Day RSO Schedule (Easy Version)

Step 1: Start Very Small (Days 1–10)

Goal: Let your body adjust

  • Dose: ¼ grain of rice
  • Time: Once at night

If you feel okay after a few days, you may take: ¼ grain in the morning + ¼ grain at night

Step 2: Slow Increase (Days 11–30)

Goal: Build tolerance without discomfort

  • Dose: ½ grain
  • Times per day: 2–3 times

Stay at this level if it feels strong. There is no rush.

Step 3: Medium Dose (Days 31–60)

Goal: Reach a helpful daily amount

  • Dose: 1 grain
  • Times per day: 3 times

Most beginners feel effects clearly at this stage.

Step 4: Full Daily Use (Days 61–90)

Goal: Maintain a steady routine

  • Total per day: Up to 1 gram total
  • Split into: 3–5 small doses

Not everyone needs the full amount. Use what feels right for your body.

Final Advice for First-Time Users

Slow progress = better experience.

Taking less RSO more consistently works better than taking too much at once.

Listen to your body.

Go at your own pace.

Best RSO Products for the 90-Day Protocol

Best Value

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Complete 90-day protocol package. Includes 60 grams of premium RSO with batch-matched lab results and dosing guide.

$1,500Complete Protocol
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60g Rick Simpson Oil full treatment package for 90-day protocol 2025

Frequently Asked Questions