RSO Dosage Guide 2025: Complete Rick Simpson Oil Protocol Chart + How to Start Safely
The original Rick Simpson protocol calls for consuming one gram per day by week 5–12, but starting too fast causes extreme drowsiness and discomfort. This updated 2025 guide gives you the safest, most effective titration schedule used by thousands of our customers.
Official 2025 Rick Simpson Oil Dosage Chart

| Weeks | Daily Dose | Total per Week | Notes |
|---|---|---|---|
| 1–2 | Rice-grain (≈ 0.1g split 3×/day) | 1–2 grams | Start low, go slow |
| 3–4 | Pea-size (≈ 0.25g split 3×/day) | 3–5 grams | Increase only if comfortable |
| 5–12 | 1 gram per day (split or night dose) | 7–8 grams | Maintenance phase |
Important Safety Note
Never exceed recommended doses. If you experience discomfort, reduce your dose and slow down the titration. Everyone's tolerance is different. Listen to your body.
How to Measure a Rice-Grain Dose Accurately

Use the syringe markings
Our 1g syringes are marked in 0.1g increments. A rice grain is approximately 0.05-0.1g.
Warm the syringe first
RSO thickens when cold. Hold in your hand for 30 seconds or run under warm water for easier dispensing.
Dispense onto food
Place the dose on a small piece of bread, cracker, or directly into peanut butter for easier consumption.
Best RSO Products for the 90-Day Protocol
10g RSO Syringe Bundle
Perfect for the 90-day protocol. Includes 10 × 1g syringes with batch-matched lab results.
