RSO Dosage Plan: Complete Beginner to Advanced Protocol
Master Rick Simpson Oil dosing with our comprehensive 90-day protocol guide

Rick Simpson Oil (RSO) dosing requires careful planning and gradual progression. This comprehensive guide provides a structured protocol from beginner to advanced levels, helping you safely navigate your RSO journey with confidence.
Quick Dosage Overview
Beginner
1/4 grain
3x daily
Week 1-2
Intermediate
1/2 grain
3x daily
Week 3-8
Advanced
1 gram
daily total
Week 9-12+

Phase 1: Beginner Protocol (Weeks 1-2)
Starting Dose: 1/4 Grain of Rice
- Size Reference: Approximately 25mg or the size of a short-grain rice piece cut into quarters
- Frequency: 3 times daily (morning, afternoon, evening before bed)
- Total Daily Dose: Approximately 75mg (25mg x 3)
Week 1-2 Schedule
| Time | Dose | Notes |
|---|---|---|
| Morning (8-9 AM) | 1/4 grain (25mg) | Take with breakfast |
| Afternoon (2-3 PM) | 1/4 grain (25mg) | Take with lunch or snack |
| Evening (9-10 PM) | 1/4 grain (25mg) | Take 1 hour before bed |
What to Expect in Week 1-2
- - Mild relaxation and potential drowsiness (especially in evening doses)
- - Slight appetite increase
- - Improved sleep quality
- - Mild digestive adjustments (normal - your body is adapting)
- - Possible mild headache (stay hydrated!)

Phase 2: Intermediate Protocol (Weeks 3-8)
Increased Dose: 1/2 Grain of Rice
- Size Reference: Approximately 50mg or half of a short-grain rice piece
- Frequency: 3 times daily (maintaining the same schedule)
- Total Daily Dose: Approximately 150mg (50mg x 3)
Week 3-8 Progression
Weeks 3-4: Double the Dose
Increase from 1/4 grain to 1/2 grain at each dosing time. Monitor how your body responds.
Tip: If you experience increased drowsiness, reduce the afternoon dose slightly and keep evening dose higher for better sleep.
Weeks 5-6: Stabilization
Maintain 1/2 grain 3x daily. Your body should now be accustomed to this level.
Notice: You may feel normal and less drowsy as tolerance builds. This is expected and positive.
Weeks 7-8: Preparation for Full Dose
Continue 1/2 grain 3x daily while preparing to potentially increase to full therapeutic dose (1 grain).
Assessment: Evaluate your symptom relief and tolerance level before progressing.
What to Expect in Weeks 3-8
- - Increased therapeutic effects for pain, inflammation, and symptom relief
- - Better tolerance - less drowsiness than initial weeks
- - Consistent sleep improvements
- - Appetite normalization
- - Potential mood stabilization and reduced anxiety
Ready to Start Your RSO Journey?
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Medical Disclaimer
This dosing guide is for educational purposes only and does not constitute medical advice. RSO is a potent cannabis extract and should be used responsibly. Consult with a healthcare professional familiar with cannabis therapeutics before beginning any RSO protocol, especially if you have pre-existing health conditions or take prescription medications. Start low, go slow, and adjust based on your individual response. Cannabis laws vary by location - ensure RSO is legal in your area before purchasing or using.